The development of liposomes as a drug delivery system has fluctuated since its introduction in the late 1960s by a. Today, they are a very useful reproduction, reagent, and tool in various scientific disciplines, including mathematics and theoretical physics, biophysics, chemistry, colloid science, biochemistry, and biology. If you are viewing this page on a mobile device or would like to print this information for offline use, we have formatted the data into an easy to read pdf. Today, they liposomes, sphereshaped vesicles consisting of one or more phospholipid bilayers, download pdf liposome. Ppt liposomes powerpoint presentation free to download id. Modes of liposome action liposomes as drug delivery systems can offer several advantages over conventional. Structurally, liposomes are concentric bilayered vesicles in which an aqueous volume is entirely enclosed by a membranous lipid bilayer mainly composed of natural or synthetic phospholipids liposomes became the predominant drug delivery and targeting system. Find powerpoint presentations and slides using the power of, find free presentations research about liposomes ppt. The vesicle is composed of a bilayer of nonionic surface active agents and hence the name niosomes. Scribd is the worlds largest social reading and publishing site. Guidancecomplianceregulatoryinformationguidancesucm199635. Since the first edition of liposomes a practical approach was published in 1990, liposome technology has become a highly successful and rapidly developing area of preclinical and clinical research. Applications of liposomes 499 although they are composed from natural substances liposomes are no exception.
Our new crystalgraphics chart and diagram slides for powerpoint is a collection of over impressively designed datadriven chart and editable diagram s guaranteed to impress any audience. Novel methods for liposome preparation sciencedirect. This shortens the circulation times of the liposomes substantially. Liposomes were discovered in the early 1960s by bangham and colleagues. Therapeutic application of liposomes liposomes in multidrug resistance multidrug resistance is often associated with the overexpression of some drugefflux pumps. Download fulltext pdf application of liposomes in medicine and drug delivery article pdf available in artificial cells 441. Endocytosis is shown in the upper left part of the cell. Today, they are a very useful model, reagent and tool in various. Ppt liposomes powerpoint presentation free to view. The lipid bilayer used in the liposomes are usually made of phospholipids and cholesterol. Remove this presentation flag as inappropriate i dont like this i like this remember as a favorite.
Introduction liposomes are simple microscopic, concentric bilayered vesicles in which an aqueous volume is entirely enclosed by a membranous lipid bilayer mainly composed of natural or synthetic phospholipids. Adapting liposomes for oral drug delivery sciencedirect. Handling of liposomes the lipids used in the preparation of liposomes are unsaturated and hence susceptible to oxidation. Wait for the extraction to finish and download your ppt. View and download powerpoint presentations on liposomes ppt. Chart and diagram slides for powerpoint beautifully designed chart and diagram s for powerpoint with visually stunning graphics and animation effects. Liposomes are spherical vesicles having an aqueous core enclosed by one or more phospholipid bilayers or lamellae. The adobe flash plugin is needed to view this content. Cpp critical packing parameter if cpp value is less than 0.
Winner of the standing ovation award for best powerpoint templates from presentations magazine. Among the lipid phospholipids are the amphoteric lipids capable of forming bilayer and hence are the integral part of the liposomal system. Liposomes consist of enclosed vesicles of concentric selfassembling lipid bilayers composed of phospholipids and cholesterols in common1. Samajs, college of pharmacy,gangapur road, nasik 422 002, maharashtra, india. Liposomes can be prepared according to different methods. A novel drug delivery system priyanka r kulkarni, jaydeep d yadav, kumar a vaidya department of pharmaceutical sciences, n. Liposomes are considered as a promising technology for a variety of pharmaceutical and industrial applications since they are amphiphilic carriers open to modifications with different functional. Applications of liposomes dr baumann cosmetics canada.
The structural main components are phospholipids and cholesterol 3. Oct 08, 2014 liposomes a novel drug delivery system slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Jan, 2014 contents of the powerpoint on liposome formation, preparation, properties and applications include. Liposomes have also been used in the treatment of metal poisoning, since the liver is the major site of heavy metal and iron accumulation. Contents of the powerpoint on liposome formation, preparation, properties and applications include.
Liposomes that contain low or high ph can be constructed such that dissolved aqueous drugs will be charged in solution i. Niosomes are a novel drug delivery system, in which the medication is encapsulated in a vesicle. While academic research of liposomes as a model membrane system has always flourished, as the exponential growth of papers can testify, the application of these findings to medically useful products has gone through several crises. At first, they were used to study biological membranes. Schematic presentation of liposome interactions with cells. Ppt liposomes powerpoint presentation free to view id.
A liposome is a spherical vesicle having at least one lipid bilayer. Liposomes a novel drug delivery system slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. The evolution of the science and technology of liposomes has been used in the development of drug carrier concept as a promising delivery system. These liposomes are composed of natural phospholipids which may be neutral or negatively charged and cholesterol. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. Jan, 2014 contents of the powerpoint on niosomes drug delivery systems include. If you continue browsing the site, you agree to the use of cookies on this website.
Definition of liposomes salient features classification of liposomes\u000b suv small unilamellar vesicles luv large unilamellar vesicles mlv multilamellar vesicles llc lamellar liquid crystalline phase mvv multivesicular vesicles liposomes are composed of one to several hundreds. Also volatile solvents such as chloroform which are used will tend to evaporate from the container. The global market for nanobased targeted drug delivery is presented by the following submarkets liposomes. Liposomes can be prepared by disrupting biological membranes such as by sonication liposomes are most often composed of phospholipids, especially phosphatidylcholine, but may also include other lipids, such as egg. Smallpdf will upload and start to work on the file right away. Pdf application of liposomes in medicine and drug delivery. Lipids are a group of compounds which are differentiated by their feature of solubility in nonpolar solvents and insolubility in water.
Definition of liposomes salient features classification of liposomes\u000b suv small unilamellar vesicles luv large unilamellar vesicles mlv multilamellar vesicles llc lamellar liquid crystalline phase mvv multivesicular vesicles liposomes are composed of one to several. We use your linkedin profile and activity data to personalize ads and to show you more relevant ads. Ppt liposome formation, preparation, properties and. Liposomes are cellular structures made up of lipid molecules. Liposomes part e is a continuation of previous methods in enzymology liposome volumes a, b, c and d. The flexibility in their behaviour can be exploited for the drug delivery through any route of administration and for any drug or material irrespective of its physicochemical. Contents of these liposomes are most often destined for lysosomes new, 1990. The use of liposomes is another way to target a specific tissue with a drug 99. Conclusions liposomes over the years have been investigated as the major drug delivery systems due to their flexibility to be tailored for varied desirable purposes.
They may vary in their dimensions, composition different phospholipids and cholesterol contents, charge resulting from the charges of the composing phospholipids, and structure multilamellar liposomes consisting of. Ppt liposomes powerpoint presentation, free download id. Since then, liposomes have made their way to the market. Since the discovery of liposomes by bangham and horne in 1964 1, the potential of liposomes as drug delivery carriers has been extensively explored via versatile administrative routes such as parenteral, oral, pulmonary, nasal, ocular and transdermal routes2. A practical approach since the first edition of liposomes a practical approach was published in 1990, liposome technology has become a highly successful and rapidly developing area of preclinical and clinical research. Liposomes, glycolipids, drug formulations, drug delivery systems. Today, they are a very useful reproduction, reagent, and tool in various. Liposomes can also be designed to deliver drugs in other ways. Liposomes manufacturing liposomes are manufactured in majority using various procedures in which the water soluble hydrophilic materials are entrapped by using aqueous solution of these materials as hydrating fluid or by addition of drugdrug solution at some stage during manufacturing of liposomes. Liposomes are most frequently classified on the basis of their size small, large and giant vesicles, number of bilayers uni, oligo and multilamellar vemuri and rhodes, 1995, vuillemard, 1991 and phospholipid charge neutral, anionic or cationic storm. Download fulltext pdf himanshi et al international journal of pharmaceutical scie nces letters 2015 vol. Conventional liposomes are distributed to a smaller volume, depending on the drug leakage from liposomes, which is a function of lipid composition and the method of drug encapsulation. Infection powerpoint on liposome formation, preparation, properties and applications include. Lipids are a distinct group of compounds, including oils, waxes, steroids, fats and similar compounds that are very much connected by their physical property rather than their chemical property.
Ppt liposomes powerpoint presentation free to download. Liposomes, sphereshaped vesicles consisting of one or more phospholipid bilayers, were first described in the mid60s. Liposomes methods and protocols 2nd edition pdf free download ebook description this second edition volume expands on the previous edition by discussing classic techniques, as well as new protocols that focus on the preparation of liposomes, lipid characterization, particle size and charge analysis, drug encapsulation, surface modification. The liposome can be used as a vehicle for administration of nutrients and pharmaceutical drugs. Characterization of liposomes the liposomes prepared were characterized by their phospholipid contents by. Download as pdf about authors devender sharma 1, aashiya aara e. Creative biostructure established an advanced and novel liposomes platform to faciliate research in membrane proteins and other scientific fields. These liposomes are often used for targeting of the reticuloendothelial system res. Liposomes, or phospholipid vesicles, are selfassembled colloidal particles that occur naturally and can be prepared artificially, as shown by bangham and his students in the mid1960s.
They are rapidly cleared from the circulation by the macrophages which are located mainly in the liver, spleen, and bone marrow. Liposomes 2 free download as powerpoint presentation. Contents introduction mechanism of liposome formation classification. As the ph naturally neutralizes within the liposome protons.
Composition of liposomes lipids lipid mix is the major component of liposomes. A free powerpoint ppt presentation displayed as a flash slide show on id. Worlds best powerpoint templates crystalgraphics offers more powerpoint templates than anyone else in the world, with over 4 million to choose from. Definition of liposomes salient features classification of liposomes \u000b suv small unilamellar vesicles luv large unilamellar vesicles mlv multilamellar vesicles llc lamellar liquid crystalline phase mvv multivesicular vesicles liposomes are composed of one to several hundreds.
Theyll give your presentations a professional, memorable appearance the kind of sophisticated look that todays audiences expect. Liposomes free download as powerpoint presentation. Phospholipids a phospholipid has two acyl chains linked to a headgroup by means of a glycerolbackbone. Search powerpoint and keynote presentations, pdf documents, powerpoint templates and diagrams on authorstream. Important as a cellular model in the study of basic biology, liposomes are also used in clinical applications such as drug delivery and virus studies. Oct 11, 2011 targeted drug delivery system liposomes.
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